Brief Information of the Compound and Protein
Compound Name
rac-7-(cyclohexylmethyl)-2-((1S,2R)-2-phenylcyclopropyl)tetrahydroimidazo[1,5-a]pyrazine-1,3(2H,5H)-dione
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PubChem ID
CID: 56670004
Canonical SMILES
O=C1C2CN(CC3CCCCC3)CCN2C(=O)N1[C@H]1C[C@@H]1c1ccccc1
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Compound Formula C22H29N3O2
Compound Structure
Protein Name
Protein smoothened
Protein Classification
Membrane receptor
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Frizzled family G protein-coupled receptor
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Smoothened receptor (frizzled family GPCR)
Uniprot ID
Q99835
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000109 COS-1 Chlorocebus aethiops (Green monkey)  1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS