Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6,8-dioxo-7-[(1S,2R)-2-phenylcyclopropyl]-N-(2-phenylpyrazol-3-yl)-3,4,9,9a-tetrahydro-1H-pyrazino[1,2-c]pyrimidine-2-carboxamide
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 PubChem ID
CID: 56680279
Canonical SMILES
O=C(Nc1ccnn1-c1ccccc1)N1CCN2C(C1)CC(=O)N([C@H]1C[C@@H]1c1ccccc1)C2=O
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Compound Formula C26H26N6O3
Compound Structure
Protein Name
 Protein Info 
Protein smoothened
Protein Classification
Membrane receptor
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Frizzled family G protein-coupled receptor
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Smoothened receptor (frizzled family GPCR)
Uniprot ID
Q99835
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000109 COS-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
IC50 = 7800 nM
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