Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[2-[6-(3-chlorophenyl)pyridin-3-yl]pyrrolidin-1-yl]-(5-methyl-1,2-oxazol-3-yl)methanone
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 PubChem ID
CID: 56683902
Canonical SMILES
Cc1cc(no1)C(=O)N1CCCC1c1ccc(nc1)-c1cccc(Cl)c1
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Compound Formula C20H18ClN3O2
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 540 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 41 nM
   TI
   LI
   LO
   TS