Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(3-chlorophenyl)-5-[1-(cyclobutanecarbonyl)pyrrolidin-2-yl]-1H-pyridin-4-one
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 PubChem ID
CID: 56663553
Canonical SMILES
Oc1cc(ncc1C1CCCN1C(=O)C1CCC1)-c1cccc(Cl)c1
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Compound Formula C20H21ClN2O2
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 7800 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 680 nM
   TI
   LI
   LO
   TS