Brief Information of the Compound and Protein
Compound Name
2,2-dimethyl-3,3-diphenyl-N-(1,3-thiazol-2-yl)propanamide
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PubChem ID
CID: 56677234
Canonical SMILES
CC(C)(C(c1ccccc1)c1ccccc1)C(=O)Nc1nccs1
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Compound Formula C20H20N2OS
Compound Structure
Protein Name
Glucocorticoid receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CL000017 HeLa Homo sapiens (Human)  1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CL000148 Huh-7 Homo sapiens (Human)  1
1
EC50 = 1357 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 2.9 nM