Brief Information of the Compound and Protein
Compound Name
4-(4-Fluoro-3-trifluoromethylphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile Hydrochloride
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PubChem ID
CID: 5328868
SID: 15750623
Canonical SMILES
COc1cc2ncc(C#N)c(Nc3ccc(F)c(c3)C(F)(F)F)c2cc1OC
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Compound Formula C19H13F4N3O2
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000254 DiFi Homo sapiens (Human)  1
1
IC50 = 158.49 nM
   TI
   LI
   LO
   TS