Brief Information of the Compound and Protein
Compound Name
(E)-4-Dimethylamino-but-2-enoic acid [4-(3-bromo-phenylamino)-3-cyano-quinolin-6-yl]-amide
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PubChem ID
CID: 10253204
SID: 15256545
Canonical SMILES
CN(C)C\C=C\C(=O)Nc1ccc2ncc(C#N)c(Nc3cccc(Br)c3)c2c1
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Compound Formula C22H20BrN5O
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000254 DiFi Homo sapiens (Human)  1
1
IC50 = 309.03 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 37.2 nM
2 IC50 = 122.9 nM
3 IC50 = 310 nM