Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(1R,2R)-2-[[5-chloro-2-[[7-methoxy-3-(2-methoxyethyl)-1,2,4,5-tetrahydro-3-benzazepin-8-yl]amino]pyrimidin-4-yl]amino]cyclohexyl]-N-ethylmethanesulfonamide
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 PubChem ID
CID: 56663174
Canonical SMILES
CCN([C@@H]1CCCC[C@H]1Nc1nc(Nc2cc3CCN(CCOC)CCc3cc2OC)ncc1Cl)S(C)(=O)=O
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Compound Formula C27H41ClN6O4S
Compound Structure
Protein Name
 Protein Info 
ALK tyrosine kinase receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
Q9UM73
Gene Name
ALK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000300 Karpas-299
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 150 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 20 nM