Brief Information of the Compound and Protein
Compound Name
2-methyl-5-(2-(pyridin-2-yl)ethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole-8-carbonitrile
    Show/Hide
PubChem ID
CID: 54585848
Canonical SMILES
CN1CCc2c(C1)c1cc(ccc1n2CCc1ccccn1)C#N
    Show/Hide
Compound Formula C20H20N4
Compound Structure
Protein Name
Histamine H1 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
P35367
Gene Name
HRH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000289 SK-N-SH Homo sapiens (Human)  1
1
IC50 = 1290 nM
   TI
   LI
   LO
   TS