Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
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 PubChem ID
CID: 135398745
SID: 14923451
Canonical SMILES
CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12
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Compound Formula C17H20N4S
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 2C
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine receptor
>
Serotonin receptor
Uniprot ID
P28335
Gene Name
HTR2C
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 5.012 nM
   TI
   LI
   LO
   TS
CL000065 HEK293-EBNA
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 7.1 nM
   TI
   LI
   LO
   TS
CL000027 tsA201
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 14 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 2.8 nM
2 Ki = 4.1 nM
3 Ki = 7.1 nM
4 Ki = 10 nM
5 Ki = 14 nM