Brief Information of the Compound and Protein
Compound Name
3-(1-methylpiperidin-4-yl)-5-(naphthalen-1-ylsulfonyl)-1H-indazole
    Show/Hide
PubChem ID
CID: 16750338
SID: 26738459
Canonical SMILES
CN1CCC(CC1)c1n[nH]c2ccc(cc12)S(=O)(=O)c1cccc2ccccc12
    Show/Hide
Compound Formula C23H23N3O2S
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  2
1
IC50 = 251 nM
   TI
   LI
   LO
   TS
2
Ki = 3.8 nM
   TI
   LI
   LO
   TS