Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-Amino-N-(2,6-bis-methylamino-pyridin-4-yl)-benzenesulfonamide
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 PubChem ID
CID: 5312144
SID: 14825549
Canonical SMILES
CNc1cc(NS(=O)(=O)c2ccc(N)cc2)cc(NC)n1
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Compound Formula C13H17N5O2S
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
Ki = 12.6 nM
   TI
   LI
   LO
   TS
2
Ki = 14.8 nM
   TI
   LI
   LO
   TS
3
Ki = 512 nM
   TI
   LI
   LO
   TS
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  2
1
Ki = 12 nM
   TI
   LI
   LO
   TS
2
Ki = 12.59 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 12 nM
2 Ki = 15.85 nM