Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-chloro-N-[4-methoxy-3-(piperazin-1-yl)phenyl]-3-methyl-1-benzothiophene-2-sulfonamide hydrochloride
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 PubChem ID
CID: 5312149
SID: 14906583
Canonical SMILES
COc1ccc(NS(=O)(=O)c2sc3ccc(Cl)cc3c2C)cc1N1CCNCC1
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Compound Formula C20H22ClN3O3S2
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  4
1
Ki = 0.8 nM
   TI
   LI
   LO
   TS
2
Ki = 1 nM
   TI
   LI
   LO
   TS
3
Ki = 1.3 nM
   TI
   LI
   LO
   TS
4
Ki = 13 nM
   TI
   LI
   LO
   TS
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  3
1
Ki = 0.631 nM
   TI
   LI
   LO
   TS
2
Ki = 1.259 nM
   TI
   LI
   LO
   TS
3
Ki = 1.3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.66 nM
2 Ki = 1 nM
3 Ki = 1.259 nM