Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(1R)-6-[(tert-butylamino)methyl]-1,2,3,4-tetrahydronaphthalen-1-yl]-2-[(2S)-1-[3-(trifluoromethyl)phenyl]sulfonylpiperidin-2-yl]acetamide
    Show/Hide
 PubChem ID
CID: 11284458
SID: 125299330
Canonical SMILES
CC(C)(C)NCc1ccc2[C@@H](CCCc2c1)NC(=O)C[C@@H]1CCCCN1S(=O)(=O)c1cccc(c1)C(F)(F)F
    Show/Hide
Compound Formula C29H38F3N3O3S
Compound Structure
Protein Name
 Protein Info 
B1 bradykinin receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Bradykinin receptor
Uniprot ID
P46663
Gene Name
BDKRB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 13 nM
   TI
   LI
   LO
   TS
CL000940 CHO-D-/aequorin
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 13 nM
   TI
   LI
   LO
   TS
2
Ki = 23 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 23 nM