Brief Information of the Compound and Protein
Compound Name
(S)-2-(6-hydroxy-6-methylheptan-2-ylamino)-4-methyl-6-(5-methyl-1H-pyrazol-3-ylamino)nicotinonitrile
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PubChem ID
CID: 24783396
SID: 49707763
Canonical SMILES
C[C@@H](CCCC(C)(C)O)Nc1nc(Nc2cc(C)n[nH]2)cc(C)c1C#N
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Compound Formula C19H28N6O
Compound Structure
Protein Name
Aurora kinase A
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
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Other protein kinase AUR family
Uniprot ID
O14965
Gene Name
AURKA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  2
1
Ki = 0.59 nM
   TI
   LI
   LO
   TS
2
Ki < 1 nM
   TI
   LI
   LO
   TS