Brief Information of the Compound and Protein
Compound Name
3-{4-[(2'-Methylbiphenyl-3-yl)methoxy]phenyl}propanic Acid
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PubChem ID
CID: 51350272
SID: 121268277
Canonical SMILES
Cc1ccccc1-c1cccc(COc2ccc(CCC(O)=O)cc2)c1
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Compound Formula C23H22O3
Compound Structure
Protein Name
Free fatty acid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Free fatty acid receptor
Uniprot ID
O14842
Gene Name
FFAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1 Homo sapiens (Human)  4
1
EC50 = 50.12 nM
   TI
   LI
   LO
   TS
2
EC50 = 81.28 nM
   TI
   LI
   LO
   TS
3
EC50 = 263.03 nM
   TI
   LI
   LO
   TS
4
EC50 = 562.34 nM
   TI
   LI
   LO
   TS
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 27 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 16.6 nM
   TI
   LI
   LO
   TS