Brief Information of the Compound and Protein
Compound Name
3-[4-(Biphenyl-3-ylmethoxy)phenyl]propanoic Acid
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PubChem ID
CID: 23136411
SID: 121268274
Canonical SMILES
OC(=O)CCc1ccc(OCc2cccc(c2)-c2ccccc2)cc1
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Compound Formula C22H20O3
Compound Structure
Protein Name
Free fatty acid receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Free fatty acid receptor
Uniprot ID
O14842
Gene Name
FFAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1 Homo sapiens (Human)  1
1
EC50 = 134.9 nM
   TI
   LI
   LO
   TS
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 260 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 676.08 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 75 nM