Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(4-{[(3-phenoxyphenyl)methyl]amino}phenyl)propanoic acid
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 PubChem ID
CID: 11595431
SID: 16698070
Canonical SMILES
OC(=O)CCc1ccc(NCc2cccc(Oc3ccccc3)c2)cc1
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Compound Formula C22H21NO3
Compound Structure
Protein Name
 Protein Info 
Free fatty acid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Free fatty acid receptor
Uniprot ID
O14842
Gene Name
FFAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 28.84 nM
   TI
   LI
   LO
   TS
2
EC50 = 47.86 nM
   TI
   LI
   LO
   TS
3
EC50 = 87.1 nM
   TI
   LI
   LO
   TS
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  4
1
EC50 = 13 nM
   TI
   LI
   LO
   TS
2
EC50 = 47.86 nM
   TI
   LI
   LO
   TS
3
EC50 = 50 nM
   TI
   LI
   LO
   TS
4
EC50 = 64.57 nM
   TI
   LI
   LO
   TS
CL000460 Flp-In-T-REx-293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 218.78 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 28.18 nM
   TI
   LI
   LO
   TS
2
EC50 = 48 nM
   TI
   LI
   LO
   TS
3
EC50 = 50.12 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 316.23 nM