Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-3-fluorobutyl]-1-benzofuran-2-carboxamide
    Show/Hide
 PubChem ID
CID: 53248209
SID: 124364617
Canonical SMILES
FC(CCNC(=O)c1cc2ccccc2o1)CN1CCN(CC1)c1cccc(Cl)c1Cl
    Show/Hide
Compound Formula C23H24Cl2FN3O2
Compound Structure
Protein Name
 Protein Info 
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000153 CHOP
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 430 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  6
1
Kd = 0.03 nM
   TI
   LI
   LO
   TS
2
Kd = 0.04 nM
   TI
   LI
   LO
   TS
3
Ki = 5.4 nM
   TI
   LI
   LO
   TS
4
Ki = 6.1 nM
   TI
   LI
   LO
   TS
5
Ki = 10 nM
   TI
   LI
   LO
   TS
6
Ki = 31.5 nM
   TI
   LI
   LO
   TS