Brief Information of the Compound and Protein
Compound Name
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-3-fluorobutyl]-1H-indole-2-carboxamide
    Show/Hide
PubChem ID
CID: 53248213
SID: 124364621
Canonical SMILES
FC(CCNC(=O)c1cc2ccccc2[nH]1)CN1CCN(CC1)c1cccc(Cl)c1Cl
    Show/Hide
Compound Formula C23H25Cl2FN4O
Compound Structure
Protein Name
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1220 nM
   TI
   LI
   LO
   TS
CL000153 CHOP Cricetulus griseus (Chinese hamster)  1
1
IC50 = 520 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 4 nM
   TI
   LI
   LO
   TS