Brief Information of the Compound and Protein
Compound Name
9-(2-aminopyrimidin-5-yl)-1-(3-chloro-4-fluorophenyl)benzo[h][1,6]naphthyridin-2(1H)-one
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PubChem ID
CID: 51351032
SID: 121269078
Canonical SMILES
Nc1ncc(cn1)-c1ccc2ncc3ccc(=O)n(-c4ccc(F)c(Cl)c4)c3c2c1
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Compound Formula C22H13ClFN5O
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42336
Gene Name
PIK3CA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000048 PC-3 Homo sapiens (Human)  1
1
EC50 = 750 nM
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   LI
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