Brief Information of the Compound and Protein
Compound Name
2-{[5,7-Dimethyl-3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidin-2-yl]oxy}ethanol
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PubChem ID
CID: 44155871
SID: 85155754
Canonical SMILES
Cc1cc(C)n2nc(OCCO)c(c2n1)S(=O)(=O)c1ccccc1
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Compound Formula C16H17N3O4S
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 283 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 477 nM
2 Ki = 22.2 nM
3 Ki = 222 nM