Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-(3-(4-((5-(hydroxymethyl)-2-methylphenyl)(methyl)amino)pyrimidin-2-ylamino)-5-morpholinophenyl)piperazin-1-ol
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 PubChem ID
CID: 54584912
Canonical SMILES
CN(c1ccnc(Nc2cc(cc(c2)N2CCN(O)CC2)N2CCOCC2)n1)c1cc(CO)ccc1C
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Compound Formula C27H35N7O3
Compound Structure
Protein Name
 Protein Info 
Ephrin type-B receptor 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Eph family
Uniprot ID
P54760
Gene Name
EPHB4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 45 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7 nM