Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[4-(3-{[4-Chloro-3-(trifluoromethyl)phenyl]amino}-3-oxopropyl)phenoxy]-N-methylpyridine-2-carboxamide
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 PubChem ID
CID: 51354603
SID: 121273552
Canonical SMILES
CNC(=O)c1cc(Oc2ccc(CCC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1
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Compound Formula C23H19ClF3N3O3
Compound Structure
Protein Name
 Protein Info 
RAF proto-oncogene serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P04049
Gene Name
RAF1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000045 A-375
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10 nM