Brief Information of the Compound and Protein
Compound Name
4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(1H)-one
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PubChem ID
CID: 939111
Canonical SMILES
Cc1cc(ccc1O)-c1cc(nc(=O)[nH]1)-c1ccccc1
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Compound Formula C17H14N2O2
Compound Structure
Protein Name
Glycogen synthase kinase-3 beta
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase GSK family
Uniprot ID
P49841
Gene Name
GSK3B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 > 5280 nM
   TI
   LI
   LO
   TS
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 17.2 nM
   TI
   LI
   LO
   TS