Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(RS)-3,4-(methylenedioxy)methamphetamine
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 PubChem ID
CID: 1615
SID: 14748568
Canonical SMILES
CNC(C)Cc1ccc2OCOc2c1
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Compound Formula C11H15NO2
Compound Structure
Protein Name
 Protein Info 
Sodium-dependent serotonin transporter
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
>
SLC06 neurotransmitter transporter family
Uniprot ID
P31645
Gene Name
SLC6A4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000241 DG-75
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 32359.37 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  5
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
2
IC50 = 2754.23 nM
   TI
   LI
   LO
   TS
3
Ki = 0.73 nM
   TI
   LI
   LO
   TS
4
Ki = 2.03 nM
   TI
   LI
   LO
   TS
5
Ki = 948 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 425 nM