Brief Information of the Compound and Protein
Compound Name
[3-(benzenesulfonyl)-7-methyl-2-methylsulfanylpyrazolo[1,5-a]pyrimidin-5-yl]methanol
    Show/Hide
PubChem ID
CID: 52918030
SID: 123054342
Canonical SMILES
CSc1nn2c(C)cc(CO)nc2c1S(=O)(=O)c1ccccc1
    Show/Hide
Compound Formula C15H15N3O3S2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 177 nM
   TI
   LI
   LO
   TS
2
Ki = 2.138 nM
   TI
   LI
   LO
   TS