Brief Information of the Compound and Protein
Compound Name
6-[(3S)-piperidin-3-yl]oxyisoquinolin-1-amine
    Show/Hide
PubChem ID
CID: 16222570
SID: 24905058
Canonical SMILES
Nc1nccc2cc(O[C@H]3CCCNC3)ccc12
    Show/Hide
Compound Formula C14H17N3O
Compound Structure
Protein Name
Rho-associated protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase DMPK family
>
AGC protein kinase ROCK subfamily
Uniprot ID
Q13464
Gene Name
ROCK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 5011.87 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2137.96 nM
2 Ki = 37.15 nM