Brief Information of the Compound and Protein
Compound Name
(1R,3S)-4-chloro-5-(3,4-difluorophenyl)-N-(3-hydroxycyclopentyl)isoxazole-3-carboxamide
    Show/Hide
PubChem ID
CID: 53318190
Canonical SMILES
O[C@H]1CC[C@H](C1)NC(=O)c1noc(c1Cl)-c1ccc(F)c(F)c1
    Show/Hide
Compound Formula C15H13ClF2N2O3
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily V member 1
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Transient receptor potential channel
Uniprot ID
Q8NER1
Gene Name
TRPV1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 404 nM
   TI
   LI
   LO
   TS