Brief Information of the Compound and Protein
Compound Name
8-chloro-2-propyl-6-(pyridin-3-ylmethoxy)isoquinolin-1-one
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PubChem ID
CID: 53326074
Canonical SMILES
CCCn1ccc2cc(OCc3cccnc3)cc(Cl)c2c1=O
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Compound Formula C18H17ClN2O2
Compound Structure
Protein Name
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 2511.89 nM
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