Brief Information of the Compound and Protein
Compound Name
N-[2-[4-[4,9-bis(difluoromethoxy)-3-oxo-1H-benzo[f]isoindol-2-yl]-3-methylphenyl]ethyl]-2-(2-methoxyphenyl)acetamide
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PubChem ID
CID: 53324453
Canonical SMILES
COc1ccccc1CC(=O)NCCc1ccc(N2Cc3c(C2=O)c(OC(F)F)c2ccccc2c3OC(F)F)c(C)c1
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Compound Formula C32H28F4N2O5
Compound Structure
Protein Name
Prostaglandin E2 receptor EP4 subtype
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Prostanoid receptor
Uniprot ID
P35408
Gene Name
PTGER4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
Ki = 0.71 nM
   TI
   LI
   LO
   TS
2
Ki = 8.4 nM
   TI
   LI
   LO
   TS