Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-chloro-2-(5-chloro-2-(5,5-dimethyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-7-ylamino)pyrimidin-4-ylamino)-N-methylbenzamide
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 PubChem ID
CID: 53325517
Canonical SMILES
CNC(=O)c1cccc(Cl)c1Nc1nc(Nc2ccc3NC(=O)CCC(C)(C)c3c2)ncc1Cl
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Compound Formula C24H24Cl2N6O2
Compound Structure
Protein Name
 Protein Info 
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000282 GTL-16
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1652 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 159 nM