Brief Information of the Compound and Protein
Compound Name
2-((8R)-8-(1-(4-fluorophenyl)-N,2,2-trimethylcyclopropanecarboxamido)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-5-yl)acetic acid
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PubChem ID
CID: 45109989
SID: 92298887
Canonical SMILES
CN([C@@H]1CCc2c(CC(O)=O)c3cccnc3n2C1)C(=O)C1(CC1(C)C)c1ccc(F)cc1
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Compound Formula C26H28FN3O3
Compound Structure
Protein Name
Prostaglandin D2 receptor 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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Prostanoid receptor
Uniprot ID
Q9Y5Y4
Gene Name
PTGDR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 4.4 nM
   TI
   LI
   LO
   TS
2
Ki = 5.1 nM
   TI
   LI
   LO
   TS