Brief Information of the Compound and Protein
Compound Name
N,N,N'-Trimethyl-N0-{[3-(1-naphthylsulfonyl)-1H-indazol-5-yl]methyl}ethane-1,2-diamine HCl
    Show/Hide
PubChem ID
CID: 53326021
Canonical SMILES
CN(C)CCN(C)Cc1ccc2[nH]nc(S(=O)(=O)c3cccc4ccccc34)c2c1.Cl
    Show/Hide
Compound Formula C23H27ClN4O2S
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  2
1
IC50 = 91 nM
   TI
   LI
   LO
   TS
2
Ki = 14 nM
   TI
   LI
   LO
   TS