Brief Information of the Compound and Protein
Compound Name
3-(4-Methoxyphenylsulfonyl)-N-(piperidin-4-yl)-1Hindazol-5-amine HCl
    Show/Hide
PubChem ID
CID: 53316821
Canonical SMILES
COc1ccc(S(=O)(=O)c2n[nH]c3ccc(NC4CCNCC4)cc23)cc1.Cl
    Show/Hide
Compound Formula C19H23ClN4O3S
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  2
1
IC50 = 126 nM
   TI
   LI
   LO
   TS
2
Ki = 9.8 nM
   TI
   LI
   LO
   TS