Brief Information of the Compound and Protein
Compound Name
3-(Naphthalen-1-ylsulfonyl)-N-(piperidin-4-ylmethyl)-1Hindazol-4-amine HCl
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PubChem ID
CID: 53321369
Canonical SMILES
Cl.O=S(=O)(c1cccc2ccccc12)c1n[nH]c2cccc(NCC3CCNCC3)c12
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Compound Formula C23H25ClN4O2S
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  2
1
IC50 = 21 nM
   TI
   LI
   LO
   TS
2
Ki = 9.5 nM
   TI
   LI
   LO
   TS