Brief Information of the Compound and Protein
Compound Name
5-(4-Methylpiperazin-1-yl)-3-(thiophen-2-ylsulfonyl)-1H-indazole
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PubChem ID
CID: 49836715
SID: 103912426
Canonical SMILES
CN1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccs1
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Compound Formula C16H18N4O2S2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  2
1
IC50 = 331 nM
   TI
   LI
   LO
   TS
2
Ki = 7.8 nM
   TI
   LI
   LO
   TS