Brief Information of the Compound and Protein
Compound Name
3-Amino-7-methyl-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one
    Show/Hide
PubChem ID
CID: 23155770
SID: 103913302
Canonical SMILES
CC1CCc2c(C1)nc(CCCCN1CCN(CC1)c1ccc3ccccc3n1)n(N)c2=O
    Show/Hide
Compound Formula C26H34N6O
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 < 10 nM
   TI
   LI
   LO
   TS