Brief Information of the Compound and Protein
Compound Name
4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-N-(5-(piperidin-4-yl)-pyridin-2-yl)pyrimidin-2-amine
    Show/Hide
PubChem ID
CID: 49840175
SID: 104166726
Canonical SMILES
CC(C)c1n[nH]c(Cl)c1-c1ccnc(Nc2ccc(cn2)C2CCNCC2)n1
    Show/Hide
Compound Formula C20H24ClN7
Compound Structure
Protein Name
Cyclin-dependent kinase 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
Uniprot ID
P11802
Gene Name
CDK4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000182 JeKo-1 Homo sapiens (Human)  2
1
IC50 = 134 nM
   TI
   LI
   LO
   TS
2
IC50 = 383 nM
   TI
   LI
   LO
   TS