Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[5-[4-(dimethylamino)piperidin-1-yl]pyridin-2-yl]-4-[5-propan-2-yl-3-(trifluoromethyl)-1H-pyrazol-4-yl]pyrimidin-2-amine
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 PubChem ID
CID: 49840306
SID: 104166862
Canonical SMILES
CC(C)c1[nH]nc(c1-c1ccnc(Nc2ccc(cn2)N2CCC(CC2)N(C)C)n1)C(F)(F)F
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Compound Formula C23H29F3N8
Compound Structure
Protein Name
 Protein Info 
Cyclin-dependent kinase 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
Uniprot ID
P11802
Gene Name
CDK4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000182 JeKo-1
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 468 nM
   TI
   LI
   LO
   TS
2
IC50 = 557 nM
   TI
   LI
   LO
   TS