Brief Information of the Compound and Protein
Compound Name
2-chloro-N-[6-(5-ethyl-4-methyl-6-prop-2-enoxypyrimidin-2-yl)pyridin-3-yl]acetamide
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PubChem ID
CID: 25154309
SID: 57248272
Canonical SMILES
CCc1c(C)nc(nc1OCC=C)-c1ccc(NC(=O)CCl)cn1
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Compound Formula C17H19ClN4O2
Compound Structure
Protein Name
Hypoxia-inducible factor 1-alpha
Protein Classification
Transcription factor
Uniprot ID
Q16665
Gene Name
HIF1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000118 U-251MG Homo sapiens (Human)  2
1
IC50 = 1800 nM
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   LI
   LO
   TS
2
IC50 = 22000 nM
   TI
   LI
   LO
   TS