Brief Information of the Compound and Protein
Compound Name
2-chloro-N-(6-(5-ethyl-4-hydroxy-6-methylpyrimidin-2-yl)pyridin-3-yl)acetamide
    Show/Hide
PubChem ID
CID: 135909416
SID: 57292656
Canonical SMILES
CCc1c(C)nc([nH]c1=O)-c1ccc(NC(=O)CCl)cn1
    Show/Hide
Compound Formula C14H15ClN4O2
Compound Structure
Protein Name
Hypoxia-inducible factor 1-alpha
Protein Classification
Transcription factor
Uniprot ID
Q16665
Gene Name
HIF1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000118 U-251MG Homo sapiens (Human)  2
1
IC50 = 1500 nM
   TI
   LI
   LO
   TS
2
IC50 = 5500 nM
   TI
   LI
   LO
   TS