Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(5-aminopyridin-2-yl)-6-(chloromethyl)pyrimidin-4-ol
    Show/Hide
 PubChem ID
CID: 135909413
SID: 57292597
Canonical SMILES
Nc1ccc(nc1)-c1nc(CCl)cc(=O)[nH]1
    Show/Hide
Compound Formula C10H9ClN4O
Compound Structure
Protein Name
 Protein Info 
Hypoxia-inducible factor 1-alpha
Protein Classification
Transcription factor
Uniprot ID
Q16665
Gene Name
HIF1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000118 U-251MG
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 6000 nM
   TI
   LI
   LO
   TS
2
IC50 = 22000 nM
   TI
   LI
   LO
   TS