Brief Information of the Compound and Protein
Compound Name
2-chloro-N-(6-(4-chloro-6-(trifluoromethyl)pyrimidin-2-yl)pyridin-3-yl)acetamide
    Show/Hide
PubChem ID
CID: 25184970
SID: 57292661
Canonical SMILES
FC(F)(F)c1cc(Cl)nc(n1)-c1ccc(NC(=O)CCl)cn1
    Show/Hide
Compound Formula C12H7Cl2F3N4O
Compound Structure
Protein Name
Hypoxia-inducible factor 1-alpha
Protein Classification
Transcription factor
Uniprot ID
Q16665
Gene Name
HIF1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000118 U-251MG Homo sapiens (Human)  2
1
IC50 = 1400 nM
   TI
   LI
   LO
   TS
2
IC50 = 10000 nM
   TI
   LI
   LO
   TS