Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-10-Dimethylaminomethyl-4-ethyl-4,9-dihydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione; hydrochloride
    Show/Hide
 PubChem ID
CID: 60700
SID: 14807035
Canonical SMILES
CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4ccc(O)c(CN(C)C)c4cc3Cn1c2=O
    Show/Hide
Compound Formula C23H23N3O5
Compound Structure
Protein Name
 Protein Info 
Hypoxia-inducible factor 1-alpha
Protein Classification
Transcription factor
Uniprot ID
Q16665
Gene Name
HIF1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000118 U-251MG
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 12 nM
   TI
   LI
   LO
   TS
2
IC50 = 60 nM
   TI
   LI
   LO
   TS
3
IC50 > 3000 nM
   TI
   LI
   LO
   TS