Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(Z)-3-(phenyl(4-(piperidin-1-ylmethyl)phenylamino)methylene)-6-(pyrrolidine-2-carbonyl)indolin-2-one
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Canonical SMILES
O=C1Nc2cc(C(=O)C3CCCN3)ccc2/C1=C(/Nc1ccc(CN2CCCCC2)cc1)c1ccccc1
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Compound Formula C32H34N4O2
Compound Structure
Protein Name
 Protein Info 
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000150 HaCaT
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 696 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 245 nM