Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(Z)-3-((4-(N-(2-(dimethylamino)ethyl)methylsulfonamido)phenylamino)(phenyl)methylene)-N-ethyl-2-oxoindoline-6-carboxamide
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 PubChem ID
SID: 16599513
Canonical SMILES
CCNC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(CCN(C)C)S(C)(=O)=O)cc1)c1ccccc1
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Compound Formula C29H33N5O4S
Compound Structure
Protein Name
 Protein Info 
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000150 HaCaT
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 108 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1 nM