Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-N-(5-chloro-1,3-benzodioxol-4-yl)-4-N-(2-methoxyethyl)-2-N-(3-methylsulfonylphenyl)pyrimidine-2,4-diamine
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 PubChem ID
CID: 52949395
Canonical SMILES
COCCN(c1ccnc(Nc2cccc(c2)S(C)(=O)=O)n1)c1c2OCOc2ccc1Cl
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Compound Formula C21H21ClN4O5S
Compound Structure
Protein Name
 Protein Info 
Ephrin type-B receptor 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Eph family
Uniprot ID
P54760
Gene Name
EPHB4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 378 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 246 nM