Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-N-(1H-indazol-4-yl)-4-N-methyl-2-N-(3-methylsulfonylphenyl)pyrimidine-2,4-diamine
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 PubChem ID
CID: 16663248
SID: 26523217
Canonical SMILES
CN(c1ccnc(Nc2cccc(c2)S(C)(=O)=O)n1)c1cccc2[nH]ncc12
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Compound Formula C19H18N6O2S
Compound Structure
Protein Name
 Protein Info 
Ephrin type-B receptor 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Eph family
Uniprot ID
P54760
Gene Name
EPHB4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 51 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 36 nM