Brief Information of the Compound and Protein
Compound Name
(3-(4-(1H-indazol-4-ylamino)pyrimidin-2-ylamino)phenyl)methanol
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PubChem ID
CID: 52944677
Canonical SMILES
OCc1cccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)c1
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Compound Formula C18H16N6O
Compound Structure
Protein Name
Ephrin type-B receptor 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Eph family
Uniprot ID
P54760
Gene Name
EPHB4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 4400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 204 nM